Teratoma

General: Also in the category of nonseminomatous germ cell tumor, teratomas are classified as mature (adult) or immature. Any component of a teratoma may become neoplastic according to its tissue of differentiation.

• Mature teratoma: 5-10% of all testicular neoplasms. Predominantly cystic and multiloculated. Foci of cartilage, neural tissue, and various types of epithelium are most common; bone is infrequent. However, all tissues must be well differentiated. The "dermoid cyst" variation (full of sebum, hair, and keratin) is common in the ovary but rare in the testis.
• Immature teratoma: Morphologic immaturity of any component of a teratoma earns it this designation (although the prognostic significance is not clear).

Gross:

Microscopic: Cellular differentiation, usually a combination of endodermal, mesodermal, and ectodermal tissues.

Differential Diagnosis:

Stains:

• Positive:
• Negative:
• Suggested, focused panel:

(1)

Cases:

---

This site contains private study notes and is under construction, constant re-organization, and updating/correction. Although effort is made to ensure the accuracy of the contents, it should NOT be considered an authoritative medical reference. Thank you.