Multiple Myeloma (plasma cell myeloma, multiple plasmacytomas)

General: Result from clonal expansion of immunoglobulin secreting, terminally differentiated B-cells. This secretory component may be termed the "M component" or monoclonal component, and may be seen prominently on serum &/or urine electrophoresis, also leading to terms such as monoclonal gammopathies, dysproteinemias, & paraproteinemias; however, these terms are considered nonspecific and may represent benign or malignant underlying causes.

Gross:

Microscopic:

Differential Diagnosis:

Stains:

• Positive:
• Negative:
• Suggested, focused panel:

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Images:


Cases:

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