Congenital Teratoma (Extragonadal teratoma)
General: The most common congenital tumor. Although associated with foci of conventional yolk sac tumor (YST), it's presence or absence does not correlate with prognosis; the predominant factor of prognostic significance is whether or not it is completely resected, and presentation prior to 30wks gestation (Congenital Teratoma. Heerema-McKenney, Am J Surg Path 2005;29;29-38).
Gross: Usually large (~10cm), with a variably soft and fibrotic pale cut surface and cystic areas. Most are sacrococcygeal.
Microscopic: Composed of a wide variety of maturing (consistent with age) and immature tissues in a myxoid stroma. Neuroepithelium, endodermal glands (enteric or respiratory), and liver are generally the most common.
Differential Diagnosis:
Stains:
- Positive:
- Negative:
- Suggested, focused panel:
((()))
Images:
Cases:
This site contains private study notes and is under construction, constant re-organization, and updating/correction. Although effort is made to ensure the accuracy of the contents, it should NOT be considered an authoritative medical reference. Thank you.